Taking images of growing cells can be challenging because of well-to-well light crosstalk inherent with many clear-bottomed microplate designs. Porvair’s new generation of Krystal glass bottom plates provides excellent light transmission and an ultra-flat optical plane—+/-15 µm—enabling high accuracy, higher sensitivity and better repeatability. Available in 24-, 96- and 384-well configurations, they come either sterilized for tissue culture to optimize cell growth or non-sterile for assay development. Deep black plates for fluorescent studies are available, together with brilliant white plates which increase sensitivity for luminescence and absorbance work. They are also fully compatible with automated liquid handling and robotic devices. Porvair Sciences Ltd.