Super-resolution is a major trend in light microscopy. The Leica SR GSD 3D is a widefield system that offers both 2D and 3D super-resolution imaging of molecules and cellular structures. Based on Ground State Depletion technology, it attains resolutions down to 20 nm in the later and 40 nm in the lateral. Equipped with a 160x high-performance objective specifically developed for super-resolution microscopy, its design is optimized for high-power laser emissions. The extremely low autofluorescence ensures a high signal-to-noise ratio, which is ideal for single molecule detection applications. User-friendly, intuitive software is included. Leica Microsystems GmbH