Software tools can help remove the complexity of experimental design, and offer quality enhancements. Umetrics recently released Modde 10, an off-the-shelf Microsoft Windows-based software package for design of experiments that offers ease-of-use. Friendly wizards take the user through all the steps of planning, analyzing, interpreting and understanding the results. In this version, the risk estimation tools for proper quality assessment have been improved by including quality by design principles. The graphical interpretation tools facilitate trouble-free implementation of QbD and estimation of the design space. Umetrics