A new accessory enhances mass spectrometry (MS) by quickly simplifying complex mass spectra, separating isobaric ions and reducing background. Called UltraFAIMS, the accessory is a miniaturized chip-based FAIMS (Field Asymmetric Ion Mobility Spectrometry) platform technology. It can be interfaced with mass spectrometers to provide an additional in-source separation stage for isobaric analytes, protein and peptide charge states, large and small proteins, isomers and conformers. Miniaturizing the chip helps to generate higher field strengths and results in a greater range of analytes that can be separated, at faster speeds, without compromising the system sensitivity. Owlstone