Several products have been launched that are suitable for the development of an ELISA detection assay for the Ebola virus.
The new products comprise three different monoclonal antibodies to the Ebola virus and 2 recombinant proteins (from theSudanandZairestrains) suitable for use in producing an optimized ELISA test kit for Ebola. An antigen-capture enzyme-linked immunosorbant assay (ELISA) test for Ebola offers the possibility of diagnosis within the first few days after symptoms begin.
Ebola, also known as Ebola hemorrhagic fever, is a disease that typically occurs in outbreaks in the tropical regions of Sub-Saharan Africa. It is caused by four different Ebola species in humans: Bundibugyo evolavirus,Sudanebolavirus,TaïForestebolavirus andZaireebolavirus, which is the most dangerous. The first known outbreak occurred in 1976 and the largest outbreak to date is the ongoing 2014 West Africa Ebola virus outbreak-which is affectingGuinea,Sierra Leone,LiberiaandNigeria.
Diagnosing Ebola can be a challenge because the early symptoms are nonspecific to Ebola infection and are often seen in patients with more commonly occurring diseases, such as malaria and typhoid fever. Accurate diagnostics are essential in controlling an outbreak. Ideally a test should be an easy-to-use and affordable solution that enables the rapid screening of suspected patients and people travelling out of an outbreak region. AMSBIO
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