Gene silencing through the use of RNAi has become a primary tool for characterizing gene involvement in disease states and interactive pathways. Containing Dicer-Substrate duplexes and provides critical improvements over the use of traditional 21mer siRNA designs the Trilencer-27 siRNA kit evades the radar of the mammalian interferon response when expressed in mammalian cells and initiate strong and specific gene silencing. Through its design (3 gene specific siRNAs and 1 negative control) it delivers the dual advantages of improved efficacy (>70% gene knockdown) and minimal interferon response.
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