Designed to evaluate optimal cell attachment to extracellular matrices and assess factors that influence cell-matrix interactions, the CultreCoat Cell Adhesion Assays measure adhesion between cells or between a cell and a surface or extracellular matrix; and have applications in many areas of disease research, including neuroscience, cancer, and inflammation, among others. They are pre-coated and ready-to-use in a black stripwell microplate format that minimizes background, allows greater sensitivity and affords flexibility in the number of samples assessed. The stripwell feature also allows multiple experiments to be conducted simultaneously using the same kit. Calcein labeling allows direct comparisons between the number of cells that are loaded and the number that adhere. Controls are provided for determining background and non-specific binding.