Designed for smaller research facilities and academic labs, the QPix 420 colony picker, has a small footprint and is suitable for protein expression, synthetic biology research, enzyme evolution, phage display, DNA sequencing and library generation and management. The pre-screening step enables objective identification and selection of colonies of interest and, combined with the system’s highly accurate robotics and organism-specific colony picking pins, ensures the right colony is picked every time, eliminating unnecessary work and expense downstream. Software includes tools to easily track sample histories throughout a workflow, and an agar height sensor that auto-calibrates picking height further increases accuracy at the picking stage.