A number of new kits have been developed for proteoglycan research. A sulfated glycosaminoglycan (GAG) quantitation kit allows easy quantification of sulfated GAGs in tissues such as cartilage, cultured chondrocytes, and chondrocyte culture solution, and is suitable for use in cartilage research and other fields. Based on a colorimetric determination method, using 1,9-dimethylmethylene blue (DMMB), the new kit is capable of measuring amounts in the 2.5-80 µg/ mL range within a wide standard curve. A new assay kit for screening of hyaluronidase inhibitors, and quantification of hyaluronidase activity in cells and other biological fluids is also available. The kit is non-radioactive, fast and easy to perform, sensitive and specific to hyaluronidase and uses a universal 96-well plate format suitable for inhibitor studies.
AMS Biotechnology (AMSBIO)