Biotech applications include monitoring of transfection, counting mitochondria, organelles and other intracellular components, and characterizing changes in cell size when changes are made these cultures. To provide more accurate measurement for these processes, Beckman Coulter has unveiled its Multisizer 4e Coulter Counter, which features a 10-µm aperture that enables users to obtain accurate count, size and mass distribution for particles and cells ranging from 0.2 to 1,600 µm. It provides high-resolution analysis for as many as 400 channels, and dynamic size measurements are provided in real-time. High-speed signal digitalization allows the use of various pulse parameters for more accurate cell and particle characterization. Beckman Coulter Life Sciences