To support determination of the ‘cold freon’ effect – the chilling sensation that inhaler users often experience, the Plume Temperature Tester PTT 1000 has been developed. Designed to measure the plume temperature of Metered-Dose Inhalers (MDIs) and nasal sprays, it incorporates a series of four thermocouples that measure a precise temperature profile of the plume at different distances from the actuator. Since the temperature can directly impact the consistency and efficiency of drug delivery, the new tester is suitable for those seeking to demonstrate therapeutic equivalence or to develop softer, warmer plumes with improved patient compliance rates. A data acquisition system under the control of an associated PC ensures efficient data capture and display, and the thermocouples are easily removed for cleaning. The new tester can be directly connected to a waste shot collector or dose uniformity sampling apparatus for streamlined integration within existing test set-ups.
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