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Micro bioreactor system enhances microbial strain screening


The ambr 15 automated micro bioreactor system is designed to enhance microbial strain screening with advanced capabilities supporting fed-batch microbial cultures. It comprises 24 single-use stirred micro bioreactors (each with an 8-12mL working volume) integrated to a user-friendly, automated workstation. The system offers parallel processing and walk-away control of the 24 micro bioreactors, providing fermentation scientists with efficient, consistent results from an enhanced early stage screening platform.

It also provides high oxygen transfer rates, rapid pH and feed additions and is suited for assessing the effects of different strains with microbial cultures. The system measures pH and DO every 12 seconds, while each micro bioreactor has pumped liquid lines for base and feed addition, enabling tight pH control and a semi-continuous feed supply. Additionally, the 10mL working volume allows multiple samplings throughout the fermentation run to assess culture growth and protein production, thus providing more detailed process understanding. Sartorius Stedim Biotech


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