The mixer mill MM 400 multi-purpose mill in the lab provides a wide range of mixing applications – it can be used for mixing and homogenizing powders and suspensions within seconds and is also suited for the disruption of biological cells as well as DNA/RNA and protein recovery.
A new adapter now allows for simultaneous cell disruption of up to 8 x 30 ml cell suspension in 50 ml Falcon tubes with glass beads. The oscillation frequency of the mill of up to 30 Hz and the process time can be individually adjusted according to application requirements.
Depending on the type of cell (yeast, bacteria, microalgae, filamentous fungi) this method is superior to manual procedures as it allows to reproducibly disrupt up to 240 ml of cell suspension within 20 seconds to 7 minutes without noticeable temperature increase. The flexible mixer mill accepts a variety of grinding jars and adapters and is also used for the homogenization of plants, soft cell tissue but also of harder sample materials.
Benefits include reproducible, efficient size reduction, mixing and homogenizing within seconds; homogenization of up to 20 x 1 ml samples or 8 x 30 ml samples per cycle; grinding in dry, wet and cryogenic mode possible; screw-top grinding jars ensure loss-free processing; and memory for 9 standard operating procedures (SOP). Retsch