SEC-MALS detector for UHPLC provides excellent sensitivity

Reduction in the cell volume of a MALS system can create technical difficulties due to the increased proximity of the laser beam to cell/sample interfaces, which leads to higher levels of stray light which can compromise instrument sensitivity. Wyatt Technology’s µDawn SEC-MALS detector for UHPLC, which will be launched at Pittcon 2014 in March, maintains the sensitivity. Its light scattering flow cell volume is less than 10 µL, and the device can be coupled to any UHPLC system to determine absolute molecular weights of any sizes of polymers, peptides and proteins or other bioloplymers directly, without resorting to column calibration or reference standard. Wyatt Technology Corporation