Utilizing SPRI (Solid Phase Reversible Immobilization)-based chemistry to speed and simplify genomic DNA size selection for next generation sequencing fragment library preparation, SPRIselect allows size distribution to be adjusted between 150 and 800 base pairs to suit the application and sequencing platform. The process can be performed manually or automated for high throughput in 96-well plates on platforms such as Beckman Coulter Life Sciences’ Biomek Workstations. Reagent kits are available in 5, 60 and 450 mL volumes and come with guidelines to assist users in customizing protocols.
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