Based on flow-based technology the 3Q Series 300 expands the level of sensitivity into the attograms with signal-to-noise enhancements greater than 5x the current state of the art instruments. Suitable for research use in mid-range, high-end and now ultra-high-end markets it has a scan speed of 27,000 points per second, a mass range of 5-700 m/z and a mass stability of 0.1 AMU in 24 hours. The systems sensitivity allows for quantitation of the most challenging small molecule assays.